Synthesis and preliminary evaluation of duocarmycin analogues incorporating the 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[2,3-e]indol-4-one (CNI) and 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[1,2-e]indol-4-one (iso-CNI) alkylation subunits 2008 Tetrahedron Prize for Creativity in Organic Chemistry. The Art of Synthesis: Methods, Strategies and Applications

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Bibliographic Details
Published inTetrahedron Vol. 65; no. 33
Main Authors GAUSS, Carla M, HAMASAKI, Akiyuki, PARRISH, Jay P, MACMILLAN, Karen S, RAYL, Thomas J, HWANG, Inkyu, BOGER, Dale L
Format Journal Article
LanguageEnglish
Published Kidlington Elsevier 2009
Subjects
Antineoplastic agents
Biological and medical sciences
Chemistry
Condensed benzenic and aromatic compounds
Exact sciences and technology
General aspects
Heterocyclic compounds
Heterocyclic compounds with only one n hetero atom and condensed derivatives
Medical sciences
Organic chemistry
Pharmacology. Drug treatments
Preparations and properties
Antineoplastic agent
Phenanthrene derivatives
Nitrogen heterocycle
Analog
Aromatic compound
Indole derivatives
Chemical synthesis
Anthracene derivatives
Alkylation
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ISSN:0040-4020
1464-5416