Tumor necrosis factor a inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation

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Bibliographic Details
Published inBiochemical pharmacology Vol. 76; no. 10; pp. 1229 - 1239
Main Authors BUCK, Isabelle, MORCEAU, Franck, CRISTOFANON, Silvia, HEINTZ, Caroline, CHATEAUVIEUX, Sébastien, REUTER, Simone, DICATO, Mario, DIEDERICH, Marc
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier 2008
Subjects
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
Erythropoiesis
Human
Erythropoietin
Enzyme
Transferases
Cytokine
GATA-1/-2
Mitogen-activated protein kinase
In vitro
Transcription factor GATA2
Signal transduction
p38
Polypeptide
Hematopoiesis
p38 Mitogen activated protein kinase
Inhibitor
FOG-1
Tumor necrosis factor α
Transcription factor GATA1
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ISSN:0006-2952
1873-2968