Mechanisms of a7-nicotinic receptor up-regulation and sensitization to donepezil induced by chronic donepezil treatment

• Published in: European journal of pharmacology Vol. 590; no. 1-3; pp. 150 - 156
• Main Authors: TAKADA-TAKATORI, Yuki, KUME, Toshiaki, OHGI, Yuta, FUJII, Takeshi, NIIDOME, Tetsuhiro, SUGIMOTO, Hachiro, AKAIKE, Akinori
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier 2008
• Subjects: Adult and adolescent clinical studies; Biological and medical sciences; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Medical sciences; Neurology; Organic mental disorders. Neuropsychology; Pharmacology. Drug treatments; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Neuroprotection; Alzheimer disease; Psychotropic; Esterases; Acetylcholinesterase; Phosphatidylinositol; Cholinergic receptor; Donepezil; Piperidine derivatives; Degenerative disease; Sensitization; Anticholinesterase agent; Mechanism of action; Nicotinic receptor; Alzheimer's disease; Nervous system diseases; Enzyme; Transferases; Enzyme inhibitor; Mitogen-activated protein kinase; Antialzheimer agent; Carboxylic ester hydrolases; Cerebral disorder; Chronic; Treatment; Kinase; Nootropic agent; Central nervous system disease; Up-regulation; Hydrolases; Phosphatidylinositol 3-kinase
• ISSN: 0014-2999; 1879-0712