Design of noncompetitive inierleukin-8 inhibitors acting on CXCR1 and CXCR2

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 50; no. 17; pp. 3984 - 4002
Main Authors MORICONI, Alessio, CESTA, Maria Candida, GALLIERA, Emanuela, DI BENEDETTO, Paola, VIGILANTE, Paolo, BERTINI, Riccardo, ALLEGRETTI, Marcello, CERVELLERA, Maria Neve, ARAMINI, Andrea, CONIGLIO, Silvia, COLAGIOIA, Sandro, BECCARI, Andrea Rosario, BIZZARRI, Cinzia, CAVICCHIA, Michela Rita, LOCATI, Massimo
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 2007
Subjects
Biological and medical sciences
Bones, joints and connective tissue. Antiinflammatory agents
Medical sciences
Pharmacology. Drug treatments
Human
Leukocyte
Antiinflammatory agent
In vitro
Modeling
Sulfonate
CXCR2 chemokine receptor
Allosteric inhibitor
Structure activity relation
Carboxylic acid
Molecular model
Affinity
Arylpropionic acid derivatives
Antagonist
Chemical synthesis
CXCR1 chemokine receptor
Interleukin 8
Macrophage
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ISSN:0022-2623
1520-4804