Increase of the LC-MS/MS sensitivity and detection limits using on-line sample preparation with large volume plasma injection Improving sensitivity in liquid chromatography-mass spectrometry

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Bibliographic Details
Published inJournal of chromatography. B, Analytical technologies in the biomedical and life sciences Vol. 825; no. 2; pp. 152 - 160
Main Authors MING LI, ALNOUTI, Yazen, LEVERENCE, Rachael, HONGGANG BI, GUSEV, Arkady I
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier Science 2005
Subjects
Analysis
Analytical, structural and metabolic biochemistry
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
General pharmacology
Medical sciences
Pharmacology. Drug treatments
On-line SPE
Solid phase extraction
LC-MS/MS
Sensitivity improvement
Sensitivity
Plasma volume
Liquid chromatography
Bioanalytical
Detection
Large volume injection
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ISSN:1570-0232
1873-376X