Oral delivery of G protein-coupled receptor modulators : An explanation for the observed class difference G-protein-coupled receptors in drug discovery

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 15; no. 16; pp. 3658 - 3664
Main Authors BEAUMONT, Kevin, SCHMID, Esther, SMITH, Dennis A
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 2005
Subjects
Biological and medical sciences
Medical sciences
Miscellaneous
Pharmacology. Drug treatments
Human
Correlation
Absorption Distribution Metabolisme Excretion
Ligand
Oral administration
Research and development
Membrane receptor
Absorption
Cell line
Modulation
Targeted drug
Colon
Pharmacokinetics
Molecular mass
Lipophilicity
Physicochemical properties
Hydrogen bond
G protein
Biological receptor
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ISSN:0960-894X
1464-3405