4-Substituted (benzo[b]thiophene-2-carbonyl)guanidines as novel Na+/M+ exchanger isoform-1 (NHE-1) inhibitors

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 15; no. 12; pp. 2998 - 3001
Main Authors LEE, Sunkyung, LEE, Hyunsuk, KYU YANG YI, BYUNG HO LEE, YOO, Sung-Eun, LEE, Kyunghee, NAM SOOK CHO
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 2005
Subjects
Biological and medical sciences
Cardiovascular system
Medical sciences
Miscellaneous
Pharmacology. Drug treatments
Nitro compound
Sodium Ions
Molecular form
Nitrile
Infarct
Rat
(Benzo[b]thiophen-2-carbonyl)guanidine
Proton
Chemical synthesis
Carrier protein
Cardioprotective
Ischemia reperfusion
Rodentia
Cardioprotective agent
Guanidines
In vitro
Biological activity
In vivo
Vertebrata
Experimental disease
Mammalia
Animal
Inhibitor
Sodium hydrogen exchanger
Cation exchanger
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ISSN:0960-894X
1464-3405