Syntheses, calcium channel agonist-antagonist modulation activities, and nitric oxide release studies of nitrooxyalkyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxyl ate racemates, enantiomers, and diastereomers

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 47; no. 1; pp. 254 - 261
Main Authors RUDONG SHAN, VELAZGUEZ, Carlos, KNAUS, Edward E
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 2004
Subjects
Biological and medical sciences
Cardiovascular system
Medical sciences
Miscellaneous
Pharmacology. Drug treatments
Heart
Nitro compound
Agonist
Calcium antagonist
Smooth muscle
Ionic channel
Racemic
Guinea pig
Structure activity relation
Enantiomer
Organic nitrate
Bicyclic compound
Aromatic compound
Dihydropyridine derivatives
Antagonist
Chemical synthesis
Release
Oxygen nitrogen heterocycle
Rodentia
Gut
Calcium Ions
Muscle contraction
Ileum
In vitro
Vertebrata
Mammalia
Nitric oxide
Diastereomer
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ISSN:0022-2623
1520-4804