New antibacterial tetrahydro-4(2H)-thiopyran and thiomorpholine S-oxide and S, S-dioxide phenyloxazolidinones Antibacterial agents: solutions for the evolving problems of resistance

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Bibliographic Details
Published inBioorganic & medicinal chemistry letters Vol. 13; no. 23; pp. 4209 - 4212
Main Authors SINGH, Upinder, RAJU, B, FRIIS, Janice M, COURTNEY, Maria, PALANDRA, Joe, HACKBARTH, Corinne J, LOPEZ, Sara, WU, Charlotte, MORTELL, Kathleen H, TRIAS, Joaquim, ZHENGYU YUAN, PATEL, Dinesh V, LAM, Stuart, GORDEEV, Mikhail F, ZHOU, Joseph, GADWOOD, Robert C, FORD, Charles W, ZURENKO, Gary E, SCHAADT, Ronda D, MORIN, Sara E, ADAMS, Wade J
Format Journal Article
LanguageEnglish
Published Oxford Elsevier 2003
Subjects
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Medical sciences
Pharmacology. Drug treatments
Linezolid
Intravenous administration
Rat
Haemophilus influenzae
Structure activity relation
Bacteria
Micrococcales
Micrococcaceae
Chemical synthesis
Oxazole derivatives
Staphylococcus aureus
Septicemia
Rodentia
Single dose
Oral administration
Bioavailability
In vitro
Pasteurellaceae
In vivo
Vertebrata
Sulfur heterocycle
Experimental disease
Mammalia
Treatment
Mouse
Animal
Oxazolidinone derivative
Sulfoxide
Carboxamide
Benzenic compound
Moraxella catarrhalis
Fluorine Organic compounds
Antibacterial agent
Pharmacokinetics
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ISSN:0960-894X
1464-3405