Poor labeling of technetium-99m RCBs (red blood cells) in vivo associated with source of normal saline used for Sn-PYP (stannous pyrophosphate) reconstitution

This letter to the editor describes a situation in which abnormal biodistribution of technetium-99m-labeled red blood cells was observed in about half of the authors' patients. The labeling procedure was reviewed, and causes for poor red blood cell (RBC) labeling with technetium-99m were groupe...

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Bibliographic Details
Published inJournal of nuclear medicine technology Vol. 18:2
Main Authors Porto, J.A., Preslar, J.S.
Format Journal Article
LanguageEnglish
Published United States 01.06.1990
Subjects
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CONTROL
DISTRIBUTION
DRUGS
ERYTHROCYTES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LABELLING
MATERIALS
NUCLEI
ODD-EVEN NUCLEI
OXYGEN COMPOUNDS
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
QUALITY CONTROL
RADIOISOTOPES
RADIOLOGY AND NUCLEAR MEDICINE
RADIOPHARMACEUTICALS
TECHNETIUM 99
TECHNETIUM ISOTOPES
TIN COMPOUNDS
TISSUE DISTRIBUTION
YEARS LIVING RADIOI 550601 > Medicine > Unsealed Radionuclides in Diagnostics
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Summary:This letter to the editor describes a situation in which abnormal biodistribution of technetium-99m-labeled red blood cells was observed in about half of the authors' patients. The labeling procedure was reviewed, and causes for poor red blood cell (RBC) labeling with technetium-99m were grouped into two categories: patient-related and product-related. Since the problem observed was undoubtedly product-related, they requested repeat quality control testing by the manufacturer. The problem of poor RBC labeling was associated with the normal saline used for reconstitution of the stannous pyrophosphate (Sn-PYP).
Bibliography:None
ISSN:0091-4916
1535-5675