A Drug-Induced Liver Injury by Western Medication

• Published in: 대한한방내과학회지, 36(1) pp. 69 - 75
• Main Author: 손창규
• Format: Journal Article
• Language: English
• Published: 대한한방내과학회 01.03.2015
• Subjects: 한의학
• ISSN: 1226-9174

Objectives: To investigate the clinical features of drug-induced liver injury (DILI) and traditional Korean medicine (TKM) -based management. Methods: A female patient diagnosed with DILI caused by Western drugs had been treated with Oriental therapies, then the subjective clinical outcome and biochemical parameters were monitored. Results: A 73-year-old female had taken Western drugs (nonsteroidal anti-inflammatory and skeletal muscle relaxants) for about 3 months, and complained of severe abdominal discomfort and tiredness. Her RUCAM score was 9, which met the criteria for DILI (AST 90 IU/L, ALT 100 IU/L, ALP 191 IU/L, and GGT 614 IU/L). She was treated with herbal drugs, moxibustion, and acupuncture, and her symptoms completely resolved, with normalized hepatic enzymes within two weeks. Conclusions: This case report provides a clinical characteristic for a typical DILI caused by Western medicine, and shows an example of a TKM-based application. KCI Citation Count: 0