Fine Needle Aspiration Cytologic Features of Well-Differentiated Papillary Mesothelioma in the Pleura - A Case Report

• Published in: Journal of pathology and translational medicine pp. 583 - 588
• Main Authors: 류한석, 진민선, 최희승, 백희종, 고재수
• Format: Journal Article
• Language: English
• Published: 대한병리학회 01.12.2009
• Subjects: 병리학
• ISSN: 2383-7837; 2383-7845

Well-differentiated papillary mesothelioma (WDPM) is a rare subtype of malignant mesothelioma, which is considered to have low malignant potential. Because of its rare occurrence in the pleura, cytopathologists are not familiar with the cytologic features of WDPM, and to date only one report regarding the cytomorphology of aspiration biopsies of WDPM in pleura has been released. The authors present the findings of fine needle aspiration cytology of WDPM in the pleura in a 53-year-old woman. Aspiration smears showed papillary clusters composed of one to three layers of surface tumor cells and a central hyalinized stromal core. Tumor cells were round, ovoid, and spindle like with minimally atypical nuclei and small conspicuous nucleoli. Mitotic activity was virtually absent. Excisional biopsy histologic and immunohistochemical findings were wholly compatible with WDPM findings. Knowledge of the specific cytologic findings of WDPM is crucial for accurate diagnosis and appropriate treatment. KCI Citation Count: 0