뇌손상 환자에서 입벌림 장애에 대한 보툴리눔 독소 A의 효과-증례보고

• Published in: Annals of rehabilitation medicine pp. 456 - 459
• Main Authors: 강윤주, 오준호, 김지성, 신성헌, 박경태
• Format: Journal Article
• Language: Korean
• Published: 대한재활의학회 01.08.2008
• Subjects: 재활의학
• ISSN: 2234-0645; 2234-0653

We report a case of severe trismus following traumatic brain injury (TBI), which was treated successfully with botulinum toxin A. Its effect evidenced long-term resolution, for over one year. A 36 year-old man with a multifocal intracranial hemorrhage was admitted for quadriplegia with dysphagia and trismus. During ten months, a nasogastric tube was placed for feeding after TBI, and at that time his upper- to-lower interincisal distance was only 1.2 cm upon voluntary mouth opening. Botulinum toxin A 450 U (DysportⓇ) was injected into both masseter, medial pterygoid and left temporalis muscles under electromyographic guidance. The interincisal distance began to improve one week after injection. He successfully underwent percutaneous endoscopic gastrostomy, dysphagia rehabilitation therapy, and dental prosthesis. More than one month after injection, oral feeding proved possible. After 1 year his interincisal distance was maintained at 2.9 cm. KCI Citation Count: 0