Group A β-hemolytic Streptococcus 인후두염과 동반된 횡문근융해증 1예

• Published in: Kidney research and clinical practice pp. 820 - 824
• Main Authors: 천석철, 장문주, 황일준, 문재현, 오소연, 채윤태, 양동호, 김경수
• Format: Journal Article
• Language: Korean
• Published: 대한신장학회 01.09.2004
• Subjects: 내과학
• ISSN: 2211-9132; 2211-9140

횡문근융해증은 1941년 2차 세계대전 당시 Bywaters 등이 압박 외상으로 인한 급성신부전으로 일주일 안에 사망한 4사체를 부검하여 신세뇨관에 색소원주 (Pigmented cast)를 발견함을 보고하였다1). 그 후 수십 년 동안 급성 신부전을 동반하거나 동반하지 않은 횡문근융해증의 여러 증례가 보고되었다. 그 원인으로 수술적 손상, 독소, 과도한 운동, 그리고 약물 남용 등이 많이 보고되었다. Bywaters and beall first reported rhabdomyolysis during World War II; the pigmented casts were found in renal tubules of 4 patients who died of acute renal failure after crushing injury. Since then, several cases of rhabdomyolysis with or without acute renal failure have been reported. The causes such as surgical injuries, excessive exercise, and drug abuse have been suggested as possible etiologies of rhabdomyolysis. Rhabdomyolysis is a clinical syndrome as a result of releasing of myocyte components from the injured striated muscles into blood stream. Clinical manifestations have ranged from asymptomatic elevation of creatinine kinase to acute renal failure which is a life threatening medical emergency. The most common cause of rhabdomyolysis is traumatic muscular injury. The others include alcohol abuse, metabolic disorder, drug, toxins, carbon monoxide poisoning, burn, vascular occlusion, excessive exercise, and bacterial or viral infections and sepsis. Among these, rhabdomyolysis caused by Group A β-hemolytic streptococcus is very rare. However, rhabdomyolysis due to pharyngitis has not been reported. We report a case of rhabdomyolysis associated with Group A β-hemolytic streptococcus. KCI Citation Count: 0