췌장 선방세포암 1예

• Published in: The Korean journal of medicine pp. 506 - 509
• Main Authors: 김규영, 이화정, 지준호, 이정림, 이원식, 박종훈, 손경락
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.04.2009
• Subjects: 내과학
• ISSN: 1738-9364; 2289-0769

최근 저자들은 매우 드문 종양인 췌장 선방세포암으로 근치적 원위부 췌장절제술과 비장절제술 시행 후 위의 단독 재발로 위전절제술과 다발성 간전이로 좌간절제술 후 보존적 capecitabine 항암화학요법을 실시하여 장기간 종양의 진행이 없는 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Acinar cell carcinoma of the pancreas is a rare tumor that constitutes 1~2% of all pancreatic cancers. The clinical and radiologic findings are inconclusive when diagnosing this disease. Acinar cell carcinoma progresses rapidly and metastasizes early, resulting in a poor prognosis. A 41-year-old man was admitted for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography (PET)-CT showed a splenic mass involving the pancreatic tail with increased 18F-fluorodeoxyglucose (18F-FDG) uptake. A primary radical distal pancreatectomy and splenectomy were carried out. The pathology revealed acinar cell carcinoma of the pancreas. Three months later, a gastric recurrence was detected and a total gastrectomy was performed. Four months later, multiple hepatic metastases were found and a left hepatectomy was carried out. During treatment with capecitabine, no evidence of tumor progression was observed for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma that did not progress for 14 months with capecitabine treatment. KCI Citation Count: 1