췌아세포종에 관한 조직병리학적 및 전자현미경적 관찰 - 한국인에 발생한 4례에 관하여

A pathological observation on four cases of pancreatoblastoma in Korean, associated with a review of Korean language literature, is performed. By light microscopy, all cases, revealed similar histological findings which support the opinion that pancreatoblastoma has a characteristic morphological fe...

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Bibliographic Details
Published inKosin Medical Journal (Online) pp. 143 - 153
Main Author 허만하
Format Journal Article
LanguageKorean
Published 고신대학교 의과대학 학술지 01.03.1988
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ISSN2005-9531
2586-7024

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Summary:A pathological observation on four cases of pancreatoblastoma in Korean, associated with a review of Korean language literature, is performed. By light microscopy, all cases, revealed similar histological findings which support the opinion that pancreatoblastoma has a characteristic morphological features and the tumor is and independent disease entity. The four cases reveals squamoid corpuscles and organoid architecture with a variable degree of acinic differentiation plus areas of sheets of cells which are less differentiated. Electron microscopic observations show an admixture of dark cells and light cells. In the cells showing acinic differentiation, a large number of electron-dense membrane bound zymogen-like granules are seen in cytoplasm. At the apical border, the cells show microvilli. The cells of the squamoid corpuscles show filamentous structure and electron dense granules in cytoplasm. A clinicopathological review of the four cases of pancreatoblastoma in Korean, with focuses on age, sex, site of neoplasm, diagnostic creteria, validity of subclassification with respect to prognosis, and significance of elevation of serum AFP etc is performed. KCI Citation Count: 0
ISSN:2005-9531
2586-7024