알레르기비염 환자에서 혈액내 가용성 CD30과 E-Selectin 농도

• Published in: Journal of rhinology pp. 112 - 115
• Main Authors: 전경호, 이재훈, 정하민, 최상헌
• Format: Journal Article
• Language: Korean
• Published: 대한비과학회 01.11.2011
• Subjects: 이비인후과학
• ISSN: 1229-1498; 2384-4361

Background and Objectives：Blood levels of soluble CD30 and soluble E-selectin are related to allergic diseases such as atopic dermatitis or asthma. However, these levels have not been well investigated in allergic rhinitis. We evaluated the association of blood concentrations of these cytokines in allergic rhinitis. Materials and Methods：The concentrations of soluble CD30 and soluble E-selectin in blood were analyzed by enzyme linked immunosorbant assay. The levels of these cytokines were compared between allergic rhinitis patients (n=48) and age-matched healthy controls (n=27), and a relationship was found with symptom severity. Result：The concentration of soluble CD30 was significantly increased in allergic rhinitis patients compared to that in normal healthy people (p=0.042). However, soluble E-selectin was not significantly increased in allergic rhinitis patients (p＞0.05). Conclusion：These results suggest a possible role of soluble CD30 in the blood of allergic rhinitis. KCI Citation Count: 0