黃連의 생리활성검증 및 화장품 소재로서의 이용가능성

• Published in: 대한본초학회지, 20(3) pp. 83 - 92
• Main Authors: 안봉전, 이진태, 이창언, 김준홍, 손준호, 곽재훈, 이진영, 박태순, 배호정, 장민정, 조철훈
• Format: Journal Article
• Language: Korean
• Published: 대한본초학회 01.09.2005
• Subjects: 한의학
• ISSN: 1229-1765; 2288-7199

Objectives : The physiological activities of Coptidis Rhizoma investigated for application as a cosmetic ingredients. Methods : We were experimented anti-oxidation effect, growth inhibition ability on cancer cells, antibacterial activity on various kinds of bacteria of skin. Results : The results were obtained as follows : Electron-donating ability(EDA) shows that Coptidis Rhizoma extracted with ethanol(94.51%) gives higher EDA in comparison to that extracted with water in 1000 ppm(63.24%). In the test of SOD-like activity, ethanol extract showed quite more activity with 81.01% in 1000 ppm, while water extract was low in 18.22%. In the inhibition activity of Xathine oxidase, ethanol extract showed higher inhibition activity compared to water extract. In measuring lipid oxidation inhibition ability using fish oil, ethanol extract in 100 ppm showed prominent ability. In the oxidation inhibition effect added with Cu2+ ion and Fe2+ ion as a oxidation promoter, ethanol extract in 1000 ppm, each in the proportion of 90% and 92%, showed high oxidation inhibition effect compared with water extract. Conclusions : The results indicated that, ethanol extract which is superior in its anti-oxidation and antibacterial effect is useful to be applied in cosmetic industry. KCI Citation Count: 18