加味防風通聖散이 고지방식이 급여 흰쥐의 체지질구성과 항산화능에 미치는 영향

• Published in: 대한본초학회지, 20(2) pp. 69 - 75
• Main Author: 이장천
• Format: Journal Article
• Language: Korean
• Published: 대한본초학회 01.06.2005
• Subjects: 한의학
• ISSN: 1229-1765; 2288-7199

Objective : Effects of Gamibangpungtongseungsan on lipid composition and antioxidant system were investigated in rat fed high fat diet. Methods : We fed control group rats high fat diet and administered normal saline for 8 weeks, and experimental group rats high fat diet and administered extract of Gamibangpungtongseungsan for 8 weeks. Results : Body weight gain, concentration of plasma triglyceride, total cholesterol, LDL-cholesterol showed a tendency to decrease in Gamibangpungtongseungsan groups. However, the concentration of HDL-cholesterol showed a tendency to increase in Gamibangpungtongseungsan groups. Plasma and liver TBARS concentration showed a low values in Gamibangpungtongseungsan groups. Activities of SOD, GSH-Px and CAT showed a tendency to increase in Gamibangpungtongseungsan groups. Conclusions : These results indicate that Gamibangpungtongseungsan has a deep inhibitory effect on lipid composition and antioxidant system. KCI Citation Count: 12