자살의 신경생물학적 이해

Suicide is a complex phenomenon resulting from interactions between individual vulnerabilities and socio environmental factors. The current review primarily focuses on research into the serotonin system, hypothalamic pituitary-adrenal axis, neurotrophic factors, lipid metabolism, and functional neur...

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Bibliographic Details
Published inTaehan Ŭisa Hyŏphoe chi pp. 85 - 92
Main Authors 김상하, 이경욱
Format Journal Article
LanguageKorean
Published 대한의사협회 01.02.2019
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Summary:Suicide is a complex phenomenon resulting from interactions between individual vulnerabilities and socio environmental factors. The current review primarily focuses on research into the serotonin system, hypothalamic pituitary-adrenal axis, neurotrophic factors, lipid metabolism, and functional neuroimaging studies. It has been found that dysfunctions in the serotonin system, hypothalamic-pituitary-adrenal axis abnormalities, and low brain derived neurotrophic factor and cholesterol levels may be linked to suicide. Additionally, recent neuroimaging studies have suggested that structural and functional abnormalities in brain areas related to cognitive and emotional regulation may be associated with suicide. More research incorporating advanced methodological approaches may shed further light on the neurobiological basis of suicide. KCI Citation Count: 0
ISSN:1975-8456
DOI:10.5124/jkma.2019.62.2.85