Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation

Chronic pancreatitis is a progressive inflammatory disease resulting from repeated episodes of acute pancreatitis that impair exocrine function and eventually produce endocrine insufficiency. Some causes of chronic pancreatitis appear to be associated with alterations in the serine–protease inhibito...

Full description

Saved in:
Bibliographic Details
Published inClinical and experimental pediatrics pp. 227 - 230
Main Authors 노은삼, Earl Kim, 고홍, 유한욱, 이범희, 김구환(서울아산병원
Format Journal Article
LanguageEnglish
Published 대한소아청소년과학회 01.05.2013
Subjects
소아과학
Online AccessGet full text

Cover

Abstract Chronic pancreatitis is a progressive inflammatory disease resulting from repeated episodes of acute pancreatitis that impair exocrine function and eventually produce endocrine insufficiency. Some causes of chronic pancreatitis appear to be associated with alterations in the serine–protease inhibitor,Kazal type 1 (SPINK1 ), cationic trypsinogen (PRSS1 ), and cystic fibrosis–transmembrane conductance regulator (CFTR ) genes, or with structural disorders in the pancreaticobiliary ductal system, such as pancreatic divisum or anomalous pancreaticobiliary ductal union (APBDU). However, it is unusual to observe both genetic alteration and structural anomaly. Here, we report 2 cases with both APBDU and a mutation in the SPINK1 genes, and we discuss the implications of these findings in clinical practice. KCI Citation Count: 1
AbstractList Chronic pancreatitis is a progressive inflammatory disease resulting from repeated episodes of acute pancreatitis that impair exocrine function and eventually produce endocrine insufficiency. Some causes of chronic pancreatitis appear to be associated with alterations in the serine–protease inhibitor,Kazal type 1 (SPINK1 ), cationic trypsinogen (PRSS1 ), and cystic fibrosis–transmembrane conductance regulator (CFTR ) genes, or with structural disorders in the pancreaticobiliary ductal system, such as pancreatic divisum or anomalous pancreaticobiliary ductal union (APBDU). However, it is unusual to observe both genetic alteration and structural anomaly. Here, we report 2 cases with both APBDU and a mutation in the SPINK1 genes, and we discuss the implications of these findings in clinical practice. KCI Citation Count: 1
Author 김구환(서울아산병원
Earl Kim
유한욱
노은삼
고홍
이범희
Author_xml – sequence: 1
  fullname: 노은삼
  organization: (연세대학교)
– sequence: 2
  fullname: Earl Kim
  organization: (연세대학교)
– sequence: 3
  fullname: 고홍
  organization: (연세대학교)
– sequence: 4
  fullname: 유한욱
  organization: (울산대학교)
– sequence: 5
  fullname: 이범희
  organization: (울산대학교)
– sequence: 6
  fullname: 김구환(서울아산병원
  organization: (울산대부설))
BackLink https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001769660$$DAccess content in National Research Foundation of Korea (NRF)
BookMark eNqVyj1rAkEQANAlJBBN_A9T2gi39xFNGSQhIojo9ctkby-OnjNhZw_Jv4-IYJ3qNW9o7lk43JlBPrXFpLTl7NGMVPdZluWFLauqHBipTwIeNShIC34XhcnDD7KPARMlUkBV8YQpNHCitANkOWInvd6aly_qCOMvNL1P2EHPJHyeDWzXi9XSwrFP5yf8bB5a7DSMrj6Z8cd7Pf-ccGzdwZMTpIvf4g7RvW3qhctfZ_alKv5R_wC86VC4
ContentType Journal Article
DBID ACYCR
DatabaseName Korean Citation Index
DatabaseTitleList
DeliveryMethod fulltext_linktorsrc
EISSN 2713-4148
EndPage 230
ExternalDocumentID oai_kci_go_kr_ARTI_298165
GroupedDBID ACYCR
AFKRA
ALMA_UNASSIGNED_HOLDINGS
BENPR
CCPQU
GROUPED_DOAJ
PIMPY
RPM
ID FETCH-nrf_kci_oai_kci_go_kr_ARTI_2981653
IngestDate Tue Nov 21 21:43:06 EST 2023
IsPeerReviewed true
IsScholarly true
Language English
LinkModel OpenURL
MergedId FETCHMERGED-nrf_kci_oai_kci_go_kr_ARTI_2981653
Notes G704-000560.2013.56.5.005
ParticipantIDs nrf_kci_oai_kci_go_kr_ARTI_298165
PublicationCentury 2000
PublicationDate 2013-05
PublicationDateYYYYMMDD 2013-05-01
PublicationDate_xml – month: 05
  year: 2013
  text: 2013-05
PublicationDecade 2010
PublicationTitle Clinical and experimental pediatrics
PublicationYear 2013
Publisher 대한소아청소년과학회
Publisher_xml – name: 대한소아청소년과학회
SSID ssj0002314554
Score 3.7626653
Snippet Chronic pancreatitis is a progressive inflammatory disease resulting from repeated episodes of acute pancreatitis that impair exocrine function and eventually...
SourceID nrf
SourceType Open Website
StartPage 227
SubjectTerms 소아과학
Title Two cases of chronic pancreatitis associated with anomalous pancreaticobiliary ductal union and SPINK1 mutation
URI https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001769660
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
ispartofPNX Clinical and Experimental Pediatrics, 2013, 56(5), , pp.227-230
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dT9swELfa8rIXBALEvpCRZmlSFNS4TmY_JmkRAw0hPiTeqsZJpwqaTKXVJP5C_izunDhNB2jAS3Syz66T-zW-c34-E_INvFo-7maZC66qckXmCVcGMnHTbiB5AjGISHG949dpcHQljq_961brocFaWsyTA33_7L6S91gVysCuuEv2DZatO4UCkMG-cAULw_V1Nv5bOBqmIUPH0GWaWwf-3qUnOJ_cOaPq6VuS-SgvpqNbpL3WarpAfiyS5zD1K1hskVuK8gXE_CeeM100vtfbrAZ2RyXqrRwT8Mce_lF762wQMemzSLJBzFQfyRUgSM6ieokW8yw7J5PpsknIoh4LQbPPlGKyv6yBPmJb46OMJaDuNVcwvAZf0GDODCI2v91oJwMsxA58JgUKEWdhv1Flho5VZkBRbJsrI4SgU85x5mXKIRh3hVdm9bQv6zIrQTXv8-r70EpK7n-mypWk3Dd6MvxdDG9mQwg9fg65kl7gt0m75_kdshYNTs_O69U-8KKFj0dOtPPZuOHAXG6Q9SryoGEJo03SyvItUgCEqIEQLca0ghBtQoguIUQRQrSGEH0KIVpCiBoIgWZKSwhRC6Ft8v1wcBkfuTBAc2sv3mJvh3TyIs92CRWB7vlCjfDkIvEj1UqnY93lKoEgQvMk-Ej2_9vdp1fofCYflsD5Qjrz2SL7Cs7gPNmrnvQju_1fYA
link.rule.ids 315,783,787
linkProvider ProQuest
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Two+cases+of+chronic+pancreatitis+associated+with+anomalous+pancreaticobiliary+ductal+union+and+SPINK1+mutation&rft.jtitle=Clinical+and+experimental+pediatrics&rft.au=%EB%85%B8%EC%9D%80%EC%82%BC&rft.au=Earl+Kim&rft.au=%EA%B3%A0%ED%99%8D&rft.au=%EC%9C%A0%ED%95%9C%EC%9A%B1&rft.date=2013-05-01&rft.pub=%EB%8C%80%ED%95%9C%EC%86%8C%EC%95%84%EC%B2%AD%EC%86%8C%EB%85%84%EA%B3%BC%ED%95%99%ED%9A%8C&rft.eissn=2713-4148&rft.spage=227&rft.epage=230&rft.externalDBID=n%2Fa&rft.externalDocID=oai_kci_go_kr_ARTI_298165