Long Term Outcomes of Left Atrial Reservoir Function in Children with a History of Kawasaki Disease

• Published in: Journal of cardiovascular imaging pp. 26 - 32
• Main Authors: 강수정, 하지현, 황서정, 김효진
• Format: Journal Article
• Language: English
• Published: 한국심초음파학회 01.03.2018
• Subjects: 내과학
• ISSN: 2586-7210; 2586-7296

Background: Decreased left atrial (LA) reservoir function is reported to be associated with elevated left ventricular (LV) enddiastolic pressure and LV diastolic dysfunction. Echocardiographic parameters that reflect LA reservoir function include LA totalemptying fraction [(maximum LA volume - minimum LA volume) / maximum LA volume], peak LA longitudinal strain(PLALS) at systole, and LA stiffness index (E/E´/PLALS). We aimed to investigate the long-term outcomes of LV diastolic functionin children with a history of Kawasaki disease (KD) (KDHx group) by assessing LA reservoir function. Methods: Retrospectively, echocardiograms performed at a mean follow-up period of 5 years after the acute phase of KD in 24children in the KDHx group were compared to those from 20 normal control subjects. LA total emptying fraction, PLALS, LAstiffness index, LV peak longitudinal systolic strain (ε), and strain rate (SR) were evaluated with conventional echocardiographicparameters. Results: The mean age at long term follow-up echocardiography in children in the KDHx group was 6.8 years. Five children(20.8%) had coronary artery lesions (CALs) in the acute stage of KD. No children showed CALs at a mean follow-up period of 5years after the acute phase of KD. There were no significant differences in the conventional echocardiographic parameters and inLA total emptying fraction, PLALS, LA stiffness index, LV peak longitudinal systolic ε, and SR, between the children in the KDHxand control group. Conclusion: LV diastolic function assessed by LA reservoir function parameters at long-term follow-up in children in the KDHxgroup appears to be favorable. KCI Citation Count: 1