항정신병제의 복용은 하지불안증후군의 위험 요소인가?
Background: Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We investigated whether antipsychotics that act as antidopaminergics increase the risk of RLS. Methods: We prospectively recruited 72 schizophrenic patients who had been medicated with antipsych...
Saved in:
| Published in | Taehan Singyŏngkwa Hakhoe chi pp. 49 - 53 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | Korean |
| Published |
대한신경과학회
01.02.2009
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Background: Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We
investigated whether antipsychotics that act as antidopaminergics increase the risk of RLS.
Methods: We prospectively recruited 72 schizophrenic patients who had been medicated with antipsychotic drugs
in a psychiatry clinic. We evaluated RLS diagnostic criteria and basic sleep habits using the Epworth Sleepiness
Scale and Pittsburgh Sleep Quality Index by face-to-face interviews using a structured questionnaire. We also
applied the Unified Parkinson’s Disease Rating Scale to evaluate extrapyramidal symptoms.
Results: Three of the 72 patients (4.2%) met RLS criteria, which is similar to the previously reported RLS incidence
among the general population in Korea.
Conclusions: There is no evidence that antipsychotics increase the risk of RLS. We believe that the mild antidopaminergic
effect of antipsychotics does not overwhelm their prominent antipsychotic effect. KCI Citation Count: 0 |
|---|---|
| AbstractList | Background: Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We
investigated whether antipsychotics that act as antidopaminergics increase the risk of RLS.
Methods: We prospectively recruited 72 schizophrenic patients who had been medicated with antipsychotic drugs
in a psychiatry clinic. We evaluated RLS diagnostic criteria and basic sleep habits using the Epworth Sleepiness
Scale and Pittsburgh Sleep Quality Index by face-to-face interviews using a structured questionnaire. We also
applied the Unified Parkinson’s Disease Rating Scale to evaluate extrapyramidal symptoms.
Results: Three of the 72 patients (4.2%) met RLS criteria, which is similar to the previously reported RLS incidence
among the general population in Korea.
Conclusions: There is no evidence that antipsychotics increase the risk of RLS. We believe that the mild antidopaminergic
effect of antipsychotics does not overwhelm their prominent antipsychotic effect. KCI Citation Count: 0 |
| Author | 정희연 남현우 차정인 홍윤호 조진환 |
| Author_xml | – sequence: 1 fullname: 남현우 organization: (서울대학교) – sequence: 2 fullname: 조진환 organization: (서울대학교) – sequence: 3 fullname: 차정인 organization: (서울대학교) – sequence: 4 fullname: 정희연 organization: (서울대학교) – sequence: 5 fullname: 홍윤호 organization: (서울대학교) |
| BackLink | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001315266$$DAccess content in National Research Foundation of Korea (NRF) |
| BookMark | eNrjYmDJy89LZWLgNDKysNC1tDCNYGHgNDQyMtU1NzAx4WDgKi7OMjAwMzExMOZk8Ho7de2bBVPfdC94vXnimwVz3sydofB689Y3s1a-mdug8HbqjDfLG15v63gztePNsrlvZ7e82roBpOTNnJa304HUrClv2nrezN3xakODPQ8Da1piTnEqL5TmZtBwcw1x9tDNK0qLz07OjM9PzATT6fnx2UXxjkEhnvFGFkamJkbGJCgFADy_WfM |
| ContentType | Journal Article |
| DBID | ACYCR |
| DatabaseName | Korean Citation Index |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| DocumentTitleAlternate | Is Antipsychotic Intake a Risk Factor for the Restless Legs Syndrome? |
| EISSN | 2288-985X |
| EndPage | 53 |
| ExternalDocumentID | oai_kci_go_kr_ARTI_282542 |
| GroupedDBID | 8JR ACYCR ALMA_UNASSIGNED_HOLDINGS |
| ID | FETCH-nrf_kci_oai_kci_go_kr_ARTI_2825423 |
| ISSN | 1225-7044 |
| IngestDate | Tue Nov 21 21:41:40 EST 2023 |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | Korean |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-nrf_kci_oai_kci_go_kr_ARTI_2825423 |
| Notes | G704-000496.2009.27.1.004 |
| ParticipantIDs | nrf_kci_oai_kci_go_kr_ARTI_282542 |
| PublicationCentury | 2000 |
| PublicationDate | 2009-02 |
| PublicationDateYYYYMMDD | 2009-02-01 |
| PublicationDate_xml | – month: 02 year: 2009 text: 2009-02 |
| PublicationDecade | 2000 |
| PublicationTitle | Taehan Singyŏngkwa Hakhoe chi |
| PublicationYear | 2009 |
| Publisher | 대한신경과학회 |
| Publisher_xml | – name: 대한신경과학회 |
| SSID | ssj0064403 ssib044734097 ssib016587353 |
| Score | 2.8639452 |
| Snippet | Background: Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We
investigated whether antipsychotics that act as... |
| SourceID | nrf |
| SourceType | Open Website |
| StartPage | 49 |
| SubjectTerms | 신경과학 |
| Title | 항정신병제의 복용은 하지불안증후군의 위험 요소인가? |
| URI | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001315266 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 대한신경과학회지, 2009, 27(1), , pp.49-53 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR1daxNBcGn75IsoKn5UieCCEFIu95HbfSp7lyuxUJ8i5C3cZyuBBEKK6IPkoUhBXwSDpTaQJ8UHoVAq_qZm8x-c2btLLqJYfbnMzczOzO4Mt3Nhdo6QR2bkBz4ERiUMzbhiJn5S8QPdrgDeiqIwCnXVxHXnaa3xzNxuWa2V1c1C1dL-INgIX_32XMn_eBVw4Fc8JfsPnp0LBQTA4F-4gofheikfU69OuUVFnXouFRrCADAHYc-hjkF5NSe5CHDgZ-WM5ihuLqjgGY1p5UwkZ2qcjYUQyF2jTGGAlAKihgOQ2aHMpJ5AcY5WVOKiUqTBvT1HCcpNZSWIzG1ymBKgobblQsOmH-_hEwg22JfUBeVb3d3OC7_c8Dt7vRiPoucRg2YynQqm9DGlWKlztAUL2F3NrMS5pbZxylmRBeiCLa2oMnFJSkqpI0Wks7BzRflfKDyvus6CXhnoqgVNl9gtOAvM1KlTVwB4xs15uAIEDCzsHjp-G1hLG1puxAqn6xC0nFmtwi6RNmnN8o20V_JyJ_BfduilXuCd8Hl7t9fu9NvwxvOkjWePTchBVo0qVrTuvPbyx2kVkkvbWGRjpmkb2N0sT1QgE1YfDp9bDelVt58U0qvmNXI1ey8qiTTIr5OVTu8G2Z6NvsnJSL6dTM_ey8mJHB-Vpmfn8virHA9Ls9GR_DKcfj-Uo0P5eTz7dHBxfoos8uRg9hF-jj_IN-_k-MfF6XDzJnm85TXdRgV0q8n9cZLGLbLW7XXj26QUaIbBk5BFMdPMxLZ4Ylp2kgSMWVFo-f4d8vCv4u5eguceubIImHWyNujvx_chCx0ED9Ra_wQ5FHTY |
| link.rule.ids | 315,786,790 |
| linkProvider | ISSN International Centre |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%ED%95%AD%EC%A0%95%EC%8B%A0%EB%B3%91%EC%A0%9C%EC%9D%98+%EB%B3%B5%EC%9A%A9%EC%9D%80+%ED%95%98%EC%A7%80%EB%B6%88%EC%95%88%EC%A6%9D%ED%9B%84%EA%B5%B0%EC%9D%98+%EC%9C%84%ED%97%98+%EC%9A%94%EC%86%8C%EC%9D%B8%EA%B0%80%3F&rft.jtitle=Taehan+Singy%C5%8Fngkwa+Hakhoe+chi&rft.au=%EB%82%A8%ED%98%84%EC%9A%B0&rft.au=%EC%A1%B0%EC%A7%84%ED%99%98&rft.au=%EC%B0%A8%EC%A0%95%EC%9D%B8&rft.au=%EC%A0%95%ED%9D%AC%EC%97%B0&rft.date=2009-02-01&rft.pub=%EB%8C%80%ED%95%9C%EC%8B%A0%EA%B2%BD%EA%B3%BC%ED%95%99%ED%9A%8C&rft.issn=1225-7044&rft.eissn=2288-985X&rft.spage=49&rft.epage=53&rft.externalDBID=n%2Fa&rft.externalDocID=oai_kci_go_kr_ARTI_282542 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1225-7044&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1225-7044&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1225-7044&client=summon |