술 전 5-알파환원효소억제제의 투여가 120W Greenlight^(TM) HPS 레이저를 이용한 광선택적 전립선기화술에 미치는 영향

• Published in: The world journal of men's health pp. 161 - 167
• Main Authors: 박현준, 박남철, 김현우, 김태남
• Format: Journal Article
• Language: Korean
• Published: 대한남성과학회 01.08.2011
• Subjects: 비뇨기과학
• ISSN: 2287-4208; 2287-4690

Purpose: To evaluate the effect of preoperative 5-alpha reductase inhibitor (ARI) administration on the operative results of photoselective vaporization of prostate with 120W GreenLight HPS laser. Materials and Methods: Data were collected from 98 benign prostatic hyperplasia (BPH) patients who underwent transurethral electrovaporization of prostate by 120W Greenlight HPS laser between Jan. 2010 and Dec. 2010. We compared the time of operation, the energy required in lasering, postoperative maximum uroflow velocity, change in residual urine volume and complications between 5-ARI administrating group and control group. Results: 56 patients administrated 5-ARI at least 3 months before surgery. 30 and 26 patients administrated finasteride and dutasteride, respectively. Mean follow up period was 4.1±1.8 months. Mean age of the subjects and mean prostate volume were not different. Mean change of postoperative hemoglobin, lasing time and energy required in lasering were greater in 5-ARI administrating group. There were 3 and 1 cases of acute urinary retension in 5-ARI administrating group and control group, respectively. Conclusions: The mean change of hemoglobin and mean energy required in lasering were greater and mean lasing time was longer in the patients who administrated 5-ARI before photoselective vaporization of prostate by 120W Greenlight HPS laser. Further investigation and extensive study will be needed to confirm these results. KCI Citation Count: 0