Carney Complex: Eleven Open Heart Operations in a Single Family

Herein, we report on a family with Carney complex. Four members of the family underwent a total of 11 open heart operations as well as 9 other operations to treat extrathoracic masses. All the family members met at least 2 major clinical criteria and 1 supplemental criterion. We analyzed their genom...

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Published inJournal of chest surgery pp. 471 - 473
Main Authors 한성준, 한우식, 강민웅, 유재현, 강신광, 나명훈
Format Journal Article
LanguageEnglish
Published 대한흉부외과학회 01.12.2017
Subjects
흉부외과학
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Summary:Herein, we report on a family with Carney complex. Four members of the family underwent a total of 11 open heart operations as well as 9 other operations to treat extrathoracic masses. All the family members met at least 2 major clinical criteria and 1 supplemental criterion. We analyzed their genomic loci, including the protein kinase A regulatory subunit 1 gene. The results revealed no specific mutations, except for a common single nucleotide polymorphism. This case series of Carney complex emphasizes the importance of close longitudinal follow-up because of the high rate of tumor recurrence irrespective of the site. Clinicians should not overlook the specific features of familial myxoma. KCI Citation Count: 0
Bibliography:https://doi.org/10.5090/kjtcs.2017.50.6.471
ISSN:2765-1606
2765-1614