네트워크 약리학적 방법론을 활용한 한의학 효능 연구 고찰
This study analyzed research methodologies based on network pharmacology to build a new system architecture optimized for Korean Medicine research. Results form studies using network pharmacology were collected and analyzed to evaluate the strength and weakness. Finally, an improved system architect...
Saved in:
| Published in | 동의생리병리학회지, 30(6) pp. 419 - 425 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | Korean |
| Published |
한의병리학회
01.12.2016
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1738-7698 2288-2529 |
| DOI | 10.15188/kjopp.2016.12.30.6.419 |
Cover
| Abstract | This study analyzed research methodologies based on network pharmacology to build a new system architecture optimized for Korean Medicine research. Results form studies using network pharmacology were collected and analyzed to evaluate the strength and weakness. Finally, an improved system architecture was proposed. Whether the predicted effects of drugs or herbs from network pharmacological analyses were in agreement with those from conventioanl knowledge of Korean Medicine was evaluated. These results were used to verify the applicability of research methodologies to the modern pharmacology and Korean Medicine respectively. Eighteen papers using TCMSP were collected and analyzed. The results suggest that the research methodology based on network pharmacology is appropriate only for the modern pharmacology but not for Korean Medicine. Information about compound-compound, herb-herb and drug-compound interactions need to be considered. We propose the modified system architecture with those information. KCI Citation Count: 0 |
|---|---|
| AbstractList | This study analyzed research methodologies based on network pharmacology to build a new system architecture optimized for Korean Medicine research. Results form studies using network pharmacology were collected and analyzed to evaluate the strength and weakness. Finally, an improved system architecture was proposed. Whether the predicted effects of drugs or herbs from network pharmacological analyses were in agreement with those from conventioanl knowledge of Korean Medicine was evaluated. These results were used to verify the applicability of research methodologies to the modern pharmacology and Korean Medicine respectively. Eighteen papers using TCMSP were collected and analyzed. The results suggest that the research methodology based on network pharmacology is appropriate only for the modern pharmacology but not for Korean Medicine. Information about compound-compound, herb-herb and drug-compound interactions need to be considered. We propose the modified system architecture with those information. KCI Citation Count: 0 |
| Author | 백종민 권영규 서한길 |
| Author_xml | – sequence: 1 fullname: 백종민 organization: (부산대학교 한의학전문대학원 양생기능의학부) – sequence: 2 fullname: 서한길 organization: (부산대학교 한의학전문대학원 양생기능의학부) – sequence: 3 fullname: 권영규 organization: (부산대학교) |
| BackLink | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002176569$$DAccess content in National Research Foundation of Korea (NRF) |
| BookMark | eNrjYmDJy89LZWCQNzTQMzQ1tLDQz87KLyjQMzIwNNMzNNIzNtAz0zMxtGRi4DQysrDQNTI1smRh4DQ0N7bQNTeztOBg4C0uzkwyMDK1MLUwM7fgZPB_3bLkbdeON7N73jauUXgzde_rZWveTp35ZkGjwusNK19vmvp64YI3c1sU3s6c82bWyrdT5ygA8Zu5M4BqFN7OWvG6a6nCm-kbXm1do_Bq84I3GzbwMLCmJeYUp_JCaW4GTTfXEGcP3byitPjs5Mz4_MRMMJ2eH59dFO8YFOIZb2hkaWJsbGZMiloABhplcQ |
| ContentType | Journal Article |
| DBID | ACYCR |
| DOI | 10.15188/kjopp.2016.12.30.6.419 |
| DatabaseName | Korean Citation Index |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| DocumentTitleAlternate | Review of Network Pharmacological Approaches on Korean Medicine |
| EISSN | 2288-2529 |
| EndPage | 425 |
| ExternalDocumentID | oai_kci_go_kr_ARTI_1294336 |
| GroupedDBID | ACYCR ADBBV ALMA_UNASSIGNED_HOLDINGS BAWUL |
| ID | FETCH-nrf_kci_oai_kci_go_kr_ARTI_12943363 |
| ISSN | 1738-7698 |
| IngestDate | Tue Nov 21 21:39:23 EST 2023 |
| IsPeerReviewed | false |
| IsScholarly | true |
| Language | Korean |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-nrf_kci_oai_kci_go_kr_ARTI_12943363 |
| Notes | http://www.hantopic.com/kjopp/KJOPP.htm G704-000534.2016.30.6.015 |
| ParticipantIDs | nrf_kci_oai_kci_go_kr_ARTI_1294336 |
| PublicationCentury | 2000 |
| PublicationDate | 2016-12 |
| PublicationDateYYYYMMDD | 2016-12-01 |
| PublicationDate_xml | – month: 12 year: 2016 text: 2016-12 |
| PublicationDecade | 2010 |
| PublicationTitle | 동의생리병리학회지, 30(6) |
| PublicationYear | 2016 |
| Publisher | 한의병리학회 |
| Publisher_xml | – name: 한의병리학회 |
| SSID | ssib025858678 ssib036278577 ssib038076306 ssib008451798 ssib012146151 |
| Score | 3.9373047 |
| Snippet | This study analyzed research methodologies based on network pharmacology to build a new system architecture optimized for Korean Medicine research. Results... |
| SourceID | nrf |
| SourceType | Open Website |
| StartPage | 419 |
| SubjectTerms | 한의학 |
| Title | 네트워크 약리학적 방법론을 활용한 한의학 효능 연구 고찰 |
| URI | https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002176569 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 동의생리병리학회지, 2016, 30(6), , pp.419-425 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR1NaxNBdGjrxYsoKn6ziHOQkJj9mo_j7nZDq6iXCr0Fs9kVG0gkpBdvhZ6KHoO2thBBxUIOQRG8-Ie6u__B92bX3bVGWj1keHnvzcz7mGTe250PQu4wZoQR17t1yJFZ3YKYt_5UWKLOQswuJI94hIniw0ds5Yl1f91eX1h8XVm1tDnqNIKXc_eV_I9XAQd-xV2y_-DZolFAAAz-hRI8DOWpfEx9lwqLOhb1l6lwqCuo71EJSE9hdOp4NYWyqbuM3A4DFNIAIyWSnCbw1ZDmNqkjFWAgGbl1JGN9aMyqqXqSSk-hHMWdteTVCihnl6LoJaMBu1DyAmBnQnHs0gex7UxOgMy8QyC4zWrgrKq2cpnz9j0qTIRLvVxsQerzNFUiCCWew3F9B4wtE0p8s1Q8DMnN4OqKzaAiM0OLul7J4qHNpVfRWFneFSULIFjeGQgKfkAMB97qQxadHVuwMs-GJ2tUmVY4TCucZfdtN0KFMwwczXauYjZ9WPn0kUUiVrYl_I9JDs_Qg6HZ2xi8wBNXdYYPtM1mgzWK-tVjxY9N978dLN4LnrefDdq9YRvSp9U2BH-WabJFcsbgPFv1sPqg-HsWljre7td3Xd0JX75UNiDzFKw8HQ5CIy7scpszXm3ATHXbbWGPfMUlanRvvj4Q8_WHUSXmWztPzuXJmuZkv7wLZKE3uEgex9sf0p3vybtX6dZUS8Y_4k_TdLybTLa0eHYYfxnH7yfJwbaW7u4ne4fpeF-DT3LwFni0dO9zvPNRS97Mjr5NtaOvk2Q2u0Tutvw1b6UOAihL_d1i5mWy1B_0wytE0-0wkAGzeTcILMnCTmB3uBmFHR4Z3aAZXiW3T27v2mmYrpOz5Vi9QZZGw83wJoTIo84t5bif9bWUmg |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%EB%84%A4%ED%8A%B8%EC%9B%8C%ED%81%AC+%EC%95%BD%EB%A6%AC%ED%95%99%EC%A0%81+%EB%B0%A9%EB%B2%95%EB%A1%A0%EC%9D%84+%ED%99%9C%EC%9A%A9%ED%95%9C+%ED%95%9C%EC%9D%98%ED%95%99+%ED%9A%A8%EB%8A%A5+%EC%97%B0%EA%B5%AC+%EA%B3%A0%EC%B0%B0&rft.jtitle=%EB%8F%99%EC%9D%98%EC%83%9D%EB%A6%AC%EB%B3%91%EB%A6%AC%ED%95%99%ED%9A%8C%EC%A7%80%2C+30%286%29&rft.au=%EB%B0%B1%EC%A2%85%EB%AF%BC&rft.au=%EC%84%9C%ED%95%9C%EA%B8%B8&rft.au=%EA%B6%8C%EC%98%81%EA%B7%9C&rft.date=2016-12-01&rft.pub=%ED%95%9C%EC%9D%98%EB%B3%91%EB%A6%AC%ED%95%99%ED%9A%8C&rft.issn=1738-7698&rft.eissn=2288-2529&rft.spage=419&rft.epage=425&rft_id=info:doi/10.15188%2Fkjopp.2016.12.30.6.419&rft.externalDBID=n%2Fa&rft.externalDocID=oai_kci_go_kr_ARTI_1294336 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1738-7698&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1738-7698&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1738-7698&client=summon |