수혈 전 항히스타민제 투여는 필요한가?

This study reviewed allergic transfusion reactions (ATRs) and the efficacy of pre-transfusion antihistamine (PreTAH) administration. Studies have shown that PreTAH does not prevent all ATRs and provides no significant benefit over non-administration groups. Instead, they may cause sedation, increase...

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Bibliographic Details
Published inTaehan Suhyŏl Hakhoe chi pp. 14 - 18
Main Author 임영애
Format Journal Article
LanguageKorean
Published 대한수혈학회 01.04.2025
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ISSN1226-9336
2383-6881
DOI10.17945/kjbt.2025.36.1.14

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Summary:This study reviewed allergic transfusion reactions (ATRs) and the efficacy of pre-transfusion antihistamine (PreTAH) administration. Studies have shown that PreTAH does not prevent all ATRs and provides no significant benefit over non-administration groups. Instead, they may cause sedation, increase the burden on medical staff, and lack cost-effectiveness. Most transfused patients do not experience ATRs; except for anaphylaxis, they pose minimal risk. Thus, the decision to administer PreTAH should carefully weigh the benefits and risks. Routine PreTAH use in all transfusion patients is not recommended. Instead, PreTAH should be reserved for patients with a high risk of allergic reactions based on their medical history and risk factors. (Korean J Blood Transfus 2025;36:14-18) Key words: Blood transfusion, Adverse effects, Histamine H1 antagonist, Premedication KCI Citation Count: 0
ISSN:1226-9336
2383-6881
DOI:10.17945/kjbt.2025.36.1.14