8, 9번 삼염색체를 가진 골수형성이상증후군과 정신분열증을 동반한 베체트병 1예

• Published in: Journal of rheumatic diseases pp. 369 - 373
• Main Authors: 백정훈, 전현정, 박윤희, 조정현, 배상균, 하유정
• Format: Journal Article
• Language: Korean
• Published: 대한류마티스학회 01.12.2013
• Subjects: 내과학
• ISSN: 2093-940X; 2233-4718

Behcet's disease (BD) is a multi-systemic inflammatory disease of unknown origin that affects nearly all organs. Recent reports of BD with myelodysplastic syndrome (MDS) often note an association with gastrointestinal involvement and trisomy 8. We herein report on a case of a 51-year-old man who had refractory schizophrenia and developed gastrointestinal BD and MDS with trisomy 8 and 9. He visited our hospital due to fever and abdominal pain. Multiple ulcerations in the colorectum were observed on colonoscopy, and he was diagnosed with intestinal BD. During the treatment of intestinal BD, anemia and thrombocytopenia developed. His bone marrow study revealed myelodysplastic syndrome (refractory anemia with ringed sideroblast) with trisomy 8 and trisomy 9. We report a rare case of intestinal BD accompanied by schizophrenia and myelodysplastic syndrome with trisomy 8 and 9. KCI Citation Count: 0