Recent advances in [18F]F-DPA as a promising translocator protein ligand for PET study

Translocator protein (TSPO) is associated with neurodegeneration diseases, and the development of potent ligands with high affinity to TSPO was valuable study for many scientists. Specially, pyrazolo[1,5-a]pyrimidine moiety has been employed for development of new TSPO ligands with good properties....

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Bibliographic Details
Published in대한방사성의약품학회지, 8(1) pp. 33 - 37
Main Author 김희권
Format Journal Article
LanguageKorean
Published 대한방사성의약품학회 01.06.2022
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Summary:Translocator protein (TSPO) is associated with neurodegeneration diseases, and the development of potent ligands with high affinity to TSPO was valuable study for many scientists. Specially, pyrazolo[1,5-a]pyrimidine moiety has been employed for development of new TSPO ligands with good properties. In this highlight review, the development of [18F]F-DPA as a promising TSPO ligand as PET tracer is described. KCI Citation Count: 0
ISSN:2384-1583
2508-3848