Adrenal crisis during a trip in a young child with septo-optic dysplasia

[Highlights]●Long-distance trips may be a precipitating factor for AC. ●Young children with SOD are at high risk of trip-associated AC. ●Prophylactic administration of a stress dose of hydrocortisone during trips may prevent AC. [Introduction] Adrenal crisis (AC) results from an absolute or relative...

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Published inClinical Pediatric Endocrinology Vol. 33; no. 2; pp. 101 - 103
Main Authors Miho Takahashi, Takeshi Sato, Satsuki Nakano, Junpei Hamada, Tomohiro Ishii, Tomonobu Hasegawa
Format Journal Article
LanguageJapanese
Published The Japanese Society for Pediatric Endocrinology 01.04.2024
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Summary:[Highlights]●Long-distance trips may be a precipitating factor for AC. ●Young children with SOD are at high risk of trip-associated AC. ●Prophylactic administration of a stress dose of hydrocortisone during trips may prevent AC. [Introduction] Adrenal crisis (AC) results from an absolute or relative cortisol deficiency (1). Previously identified precipitating factors for AC encompasses infection, surgery, and psychological stress (1). While a previous study indicated trip as a potential precipitating factor for AC (2), there is a lack of information regarding individuals susceptible to trip-associated AC. Herein, we report a case involving a young child with septo-optic dysplasia (SOD) who developed AC during a trip. [Case Report] The patient was a 16-mo-old Japanese diagnosed with SOD and complicated by deficiencies in adrenocorticotropin and thyrotropin, along with intellectual disability.
ISSN:0918-5739