1E-04 Deficiency mapping of genome regions responsible for developmental stability

Instability of phenotypic traits of organisms results from the perturbations of developmental processes. It is important for organisms to buffer perturbations during development and stabilize the final morphological traits. In this study, we used) Drosophila melanogaster as a study material, and scr...

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Bibliographic Details
Published inGenes & Genetic Systems Vol. 85; no. 6; p. 430
Main Authors TAKAHASHI Kazuo, OKADA Yasukazu, TERAMURA Kouhei
Format Journal Article
LanguageJapanese
Published The Genetics Society of Japan 2010
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Summary:Instability of phenotypic traits of organisms results from the perturbations of developmental processes. It is important for organisms to buffer perturbations during development and stabilize the final morphological traits. In this study, we used) Drosophila melanogaster as a study material, and screened genome regions responsible for developmental stability using 450 deficiency strains with the identical genetic background. We evaluated the developmental stability using the stability of bristle and wing morphological traits as indicators. As a result, we found multiple regions having significant effect on developmental stability, and many of them had trait specific effect. These results suggest that developmental stability is not regulated by a few machineries with general effect, but by multiple machineries with trait specific effect.
ISSN:1341-7568
1880-5779