Paraneoplastic demyelination in the brain presenting as a clinically occult non-Hodgkin's lymphoma

Non-Hodgkin's lymphoma (NHL) may initially present with atypical neurological manifestations, including paraneoplastic neurological syndromes. Herein, we report the case showing an initial manifestation of systemic NHL with paraneoplastic demyelination in the brain that initially mimicked the s...

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Bibliographic Details
Published inAnnals of clinical neurophysiology Vol. 21; no. 2; pp. 108 - 112
Main Authors Son, Hyoshin, Choi, Jongsuk, Kim, Sung Un, Park, Kyung Seok
Format Journal Article
LanguageKorean
Published 2019
Subjects
Non-Hodgkin lymphoma
Demyelinating diseases
Paraneoplastic syndrome
Occult malignancy
Diffuse large B-cell lymphoma
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Summary:Non-Hodgkin's lymphoma (NHL) may initially present with atypical neurological manifestations, including paraneoplastic neurological syndromes. Herein, we report the case showing an initial manifestation of systemic NHL with paraneoplastic demyelination in the brain that initially mimicked the symptoms of stroke, seizure, and brain tumor. A high index of suspicion and timely diagnostic workup is required to prevent diagnostic delay and commence proper management of the condition. In this situation, a whole-body FDG PET/CT could be useful to screen for occult malignancy.
Bibliography:KISTI1.1003/JNL.JAKO201928965448222
ISSN:2508-691X
2508-691X