Congenital Tuberculosis as a Result of Disseminated Maternal Disease: Case Report

Although tuberculosis is highly prevalent worldwide, congenital tuberculosis is one of the least common manifestations of the disease. The diagnosis is usually difficult because of the non-specific clinical presentation and the lack of awareness of maternal disease prior to pregnancy and delivery. W...

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Published inTuberculosis and respiratory diseases Vol. 78; no. 4; pp. 450 - 454
Main Authors Hoyos-Orrego, Alvaro, Trujillo-Honeysberg, Monica, Diazgranados-Cuenca, Lucy
Format Journal Article
LanguageKorean
Published 2015
Subjects
Pregnancy
Tuberculosis
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Summary:Although tuberculosis is highly prevalent worldwide, congenital tuberculosis is one of the least common manifestations of the disease. The diagnosis is usually difficult because of the non-specific clinical presentation and the lack of awareness of maternal disease prior to pregnancy and delivery. We present the case of a preterm neonate with congenital tuberculosis, born to a previously healthy mother who had developed severe disseminated tuberculosis during her pregnancy. Once the diagnosis was confirmed in the mother, the congenital infection was confirmed by isolation of Mycobacterium tuberculosis in gastric aspirates, and positive polymerase chain reaction in a cerebrospinal fluid examination. Treatment for tuberculosis with a four-drug regimen resulted in an adequate clinical response in both the mother and infant.
Bibliography:KISTI1.1003/JNL.JAKO201532751505548
ISSN:1738-3536
2005-6184