Synapsin Isoforms and Synaptic Vesicle Trafficking

Synapsins were the first presynaptic proteins identified and have served as the flagship of the presynaptic protein field. Here we review recent studies demonstrating that different members of the synapsin family play different roles at presynaptic terminals employing different types of synaptic ves...

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Bibliographic Details
Published inMolecules and cells Vol. 38; no. 11; pp. 936 - 940
Main Authors Song, Sang-Ho, Augustine, George J
Format Journal Article
LanguageKorean
Published 2015
Subjects
presynaptic terminals
synaptic vesicles
neurotransmitter release
synapsins
vesicle trafficking
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Summary:Synapsins were the first presynaptic proteins identified and have served as the flagship of the presynaptic protein field. Here we review recent studies demonstrating that different members of the synapsin family play different roles at presynaptic terminals employing different types of synaptic vesicles. The structural underpinnings for these functions are just beginning to be understood and should provide a focus for future efforts.
Bibliography:KISTI1.1003/JNL.JAKO201501255363551
ISSN:1016-8478
0219-1032