Compounds from the Aerial Parts of Aceriphyllum rossii and Their Cytotoxic Activity
The purification of the MeOH extracts from the aerial parts of Aceriphyllum rossii Engler (Saxifragaceae) using column chromatography furnished fourteen compounds (1 - 14). The chemical structures of the isolated compounds were determined using mainly nuclear magnetic resonance spectra and mass spec...
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Published in | Natural product sciences Vol. 20; no. 3; pp. 146 - 151 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Korean |
Published |
2014
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Subjects | |
Online Access | Get full text |
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Summary: | The purification of the MeOH extracts from the aerial parts of Aceriphyllum rossii Engler (Saxifragaceae) using column chromatography furnished fourteen compounds (1 - 14). The chemical structures of the isolated compounds were determined using mainly nuclear magnetic resonance spectra and mass spectrometry. All the isolated compounds were tested for their cytotoxic activity against LH-60, MCF-7 and HeLa cancer cells in vitro using a MTT assay method. Compounds possessing an olean-triterpenoid skeleton entirely exhibit dose dependent cytotoxic activity. These findings partially confirmed the anticancer effect of this medicinal plant, suggesting a further study on the anticancer potential of the triterpenoid structure in compounds from this plant. |
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Bibliography: | KISTI1.1003/JNL.JAKO201430754388365 |
ISSN: | 1226-3907 |