Expression of Proteasome Activator REGγ in Human Laryngeal Carcinoma and Associations with Tumor Suppressor Proteins

• Published in: Asian Pacific journal of cancer prevention : APJCP Vol. 13; no. 6; pp. 2699 - 2703
• Main Authors: Li, Li-Ping, Cheng, Wei-Bo, Li, Hong, Li, Wen, Yang, Hui, Wen, Ding-Hou, Tang, Yue-Di
• Format: Journal Article
• Language: Korean
• Published: 2012
• Subjects: REG{\gamma}; laryngeal carcinoma; p21; p53

The functional significance of the proteasome activator $REG{\gamma}$ in the regulation of cell proliferation and apoptosis has been recognized. However, pathological contributions to tumor development remain to be elucidated. Both oncogenic proteins and tumor suppressors are targeted by $REG{\gamma...