Anti-inflammatory Effect of Bumblebee Alcohol Extracts in CFA-Induced Rat Edema

In this study, we prepared alcohol extracts of the larva, pupa, queen, and cocoon (clony) of B. ignitus, B. terrestris, and B. h. sapporoensis, and tested the anti-inflammatory activity of the extracts by using a rat model of adjuvant-induced edema. The extracts derived from the queen of B. ignitus,...

Full description

Saved in:
Bibliographic Details
Published inToxicological research (Seoul) Vol. 28; no. 4; pp. 249 - 253
Main Authors Ahn, Mi Young, Han, Jea Woong, Yoon, Hyung Joo, Hwang, Jae Sam, Yun, Eun Young
Format Journal Article
LanguageKorean
Published 2012
Subjects
Edema
Bumblebee alcohol extract
Online AccessGet full text

Cover

More Information
Summary:In this study, we prepared alcohol extracts of the larva, pupa, queen, and cocoon (clony) of B. ignitus, B. terrestris, and B. h. sapporoensis, and tested the anti-inflammatory activity of the extracts by using a rat model of adjuvant-induced edema. The extracts derived from the queen of B. ignitus, the queen of B. terrestris, and the cocoon of B. ignitus decreased hind paw edema after 1 day of i.p. administration. These extracts also induced vasorelaxation and NO production in calf pulmonary artery endothelial cells. These results suggest that bumblebee alcohol extracts has anti-inflammatory and vasorelaxant properties.
Bibliography:KISTI1.1003/JNL.JAKO201205061579372
ISSN:1976-8257
2234-2753