Age specific serum anti-M$\ddot{u}$llerian hormone levels in 1,298 Korean women with regular menstruation

• Published in: Clinical and experimental reproductive medicine Vol. 38; no. 2; pp. 93 - 97
• Main Authors: Yoo, Ji-Hee, Kim, Hye-Ok, Cha, Sun-Wha, Park, Chan-Woo, Yang, Kwang-Moon, Song, In-Ok, Koong, Mi-Kyoung, Kang, Inn-Soo
• Format: Journal Article
• Language: Korean
• Published: 2011
• Subjects: Anti-M $\ddot{u}$llerian Hormone; Human; Ovarian Reserve; Korean
• ISSN: 2233-8233; 2233-8241

Objective: To determine the age specific serum anti-M$\ddot{u}$llerian hormone (AMH) reference values in Korean women with regular menstruation. Methods: Between May, 2010 and January, 2011, the serum AMH levels were evaluated in a total of 1,298 women who have regular menstrual cycles aged between 20 and 50 years. Women were classified into 6 categories by age: 20-31 years, 32-34 years, 35-37 years, 38-40 years, 41-43 years, above 43 years. Measurement of serum AMH was measured by commercial enzyme-linked immunoassay. Results: The serum AMH levels correlated negatively with age. The median AMH level of each age group was 4.20 ng/mL, 3.70 ng/mL, 2.60 ng/mL, 1.50 ng/mL, 1.30 ng/mL, and 0.60 ng/mL, respectively. The AMH values in the lower 5th percentile of each age group were 1.19 ng/mL, 0.60 ng/mL, 0.42 ng/mL, 0.27 ng/mL, 0.14 ng/mL, and 0.10 ng/mL, respectively. Conclusion: This study determined reference values of serum AMH in Korean women with regular menstruation. These values can be applied to clinical evaluation and treatment of infertile women.