Radiography, Bone Scan, and F-18 FDG PET/CT Imaging Findings in a Patient with Paget's Disease

• Published in: Nuclear medicine and molecular imaging Vol. 44; no. 1; pp. 87 - 89
• Main Authors: Park, Eun-Tae, Kim, Sung-Eun
• Format: Journal Article
• Language: Korean
• Published: 2010
• Subjects: Paget's disease; {18}F$-FDG PET/CT; Bone scintigraphy
• ISSN: 1869-3474; 1869-3482

Background A 52-year-old female patient sought evaluation at our hospital for an incidental abnormal finding on an abdominal radiograph. Methods The initial radiograph showed irregular sclerotic changes involving the right pelvic bone. At the same time, bone scintigraphy showed intense hot uptake in the right iliac and pubic bones. CT images showed characteristic thickening of the pelvic brim, suggesting the mixed phase of Paget's disease. Results The level of alkaline phosphatase (ALP) was 266 IU/l. $^{18}F$-FDG PET/CT images also showed diffusely increased $^{18}F$-FDG uptake in the right pelvic bone. However, the findings of $^{18}F$-FDG PET/CT were less notable than those of bone scintigraphy. Conclusion We report the imaging findings of a patient with Paget's disease evaluated by radiography, bone scintigraphy, and $^{18}F$-FDG PET/CT.