A Brief Overview of Escherichia coli O157:H7 and Its Plasmid O157

Enterohemorrhagic Escherichia coli O157:H7 is a major foodborne pathogen causing severe disease in humans worldwide. Healthy cattle are a reservoir of E. coli O157:H7, and bovine food products and fresh produce contaminated with bovine waste are the most common sources for disease outbreaks in the U...

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Bibliographic Details
Published inJournal of microbiology and biotechnology Vol. 20; no. 1; pp. 5 - 14
Main Authors Lim, Ji-Youn, Yoon, Jang-W, Hovde, Carolyn J
Format Journal Article
LanguageKorean
Published 2010
Subjects
coli O157:H7
E
pO157
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Summary:Enterohemorrhagic Escherichia coli O157:H7 is a major foodborne pathogen causing severe disease in humans worldwide. Healthy cattle are a reservoir of E. coli O157:H7, and bovine food products and fresh produce contaminated with bovine waste are the most common sources for disease outbreaks in the United States. E. coli O157:H7 also survives well in the environment. The abilities to cause human disease, colonize the bovine gastrointestinal tract, and survive in the environment require that E. coli O157:H7 adapt to a wide variety of conditions. Three major virulence factors of E. coli O157:H7 have been identified including Shiga toxins, products of the pathogenicity island called the locus of enterocyte effacement, and products of the F-like plasmid pO157. Among these virulence factors, the role of pO157 is least understood. This review provides a board overview of E. coli O157:H7 with an emphasis on pO157.
Bibliography:KISTI1.1003/JNL.JAKO201014035210167
ISSN:1017-7825
1738-8872