Investigation of Klebsiella pneumoniae Isolates Producing SHV-12 and SHV-11 ${\beta}$-Lactamases in Korean Hospitals

Of 143 clinical isolates of Klebsiella pneumoniae collected from Korean non-tertiary hospitals, 24 (16.8%) showed an extended-spectrum ${\beta}$-lactamase-positive phenotype. PCR and sequence analysis revealed the presence of TEM-116 (n=13), CTX-M-3 (n=5), CTX-M-14 (n=2), CTX-M-15 (n=3), and SHV-12...

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Bibliographic Details
Published inJournal of microbiology and biotechnology Vol. 19; no. 9; pp. 1065 - 1069
Main Authors Lee, Kyeong-Min, Yoo, Jae-Il, Yoo, Yong-Sun, Yoo, Jung-Sik, Chung, Gyung-Tae, Ahn, Tae-In, Lee, Yeong-Seon
Format Journal Article
LanguageKorean
Published 2009
Subjects
extended-spectrum ${\beta}$-lactamase
SHV-11
SHV-12
Klebsiella pneumoniae
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Summary:Of 143 clinical isolates of Klebsiella pneumoniae collected from Korean non-tertiary hospitals, 24 (16.8%) showed an extended-spectrum ${\beta}$-lactamase-positive phenotype. PCR and sequence analysis revealed the presence of TEM-116 (n=13), CTX-M-3 (n=5), CTX-M-14 (n=2), CTX-M-15 (n=3), and SHV-12 (n=16). Each of the 24 isolates encoded more than one ${\beta}$-lactamase, and seven isolates (29%) harbored two different SHV-type ${\beta}$-lactamase genes ($bla_{SHV-11}$ and $bla_{SHV-12}$) bounded by insertion sequence IS26 in a single transferable plasmid.
Bibliography:KISTI1.1003/JNL.JAKO200933063803247
ISSN:1017-7825
1738-8872