Synthesis and Antimicrobial Activity of New Substituted Anili-nobenzimidazoles

A series of benzimidazole derivatives carrying different heterocycles such as 1,2,3-thiadiazole, 1,3,4-thiadiazole, thiazolidine, 2,3-dihydro-thiazole, 1,3,4-oxadiazole, semicarbazone and substituted thiosemi-carbazones were synthesized. Also a series of 1-methylbenzimidazole carrying hydroxy ethyl-...

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Bibliographic Details
Published inArchives of pharmacal research Vol. 25; no. 3; pp. 250 - 257
Main Authors Nofal, Z.M, Fahmy, H.H, Mohamed, H.S
Format Journal Article
LanguageKorean
Published 2002
Subjects
1,2,3-Thiadiazol
Substituted thiosemicarbazones
Benzoyl hydrazide
Oxadiazol
Semicarbazone
Sulfonyl hydrazide
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Summary:A series of benzimidazole derivatives carrying different heterocycles such as 1,2,3-thiadiazole, 1,3,4-thiadiazole, thiazolidine, 2,3-dihydro-thiazole, 1,3,4-oxadiazole, semicarbazone and substituted thiosemi-carbazones were synthesized. Also a series of 1-methylbenzimidazole carrying hydroxy ethyl-amide, substituted sulfonyl hydrazide and benzoyl hydrazide from aminobenzoyl group at position 2 of 1-methylbenzimidazole were synthesized. The antimicrobial evaluation of some of the new compounds was carried out.
Bibliography:KISTI1.1003/JNL.JAKO200211922262388
ISSN:0253-6269
1976-3786