Synthesis of 2-Alkyl-substituted-$N^{6}$-methyladenine Derivatives as Potential Adenosine Receptor Ligand

2-(1-Hexynyl), 2-((E)-1-hexenyl) and $2-(n-hexyl)-N^{6}$-methyladenines were synthesized, starting from 2-amino-6-chloropurine using palladium-catalyzed coupling as a key step as potential adenosineo receptor ligand.

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Bibliographic Details
Published inArchives of pharmacal research Vol. 24; no. 6; pp. 508 - 513
Main Author Kim, Hea-Ok
Format Journal Article
LanguageKorean
Published 2001
Subjects
Palladium-catalyzed coupling
Adenosine receptors
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Summary:2-(1-Hexynyl), 2-((E)-1-hexenyl) and $2-(n-hexyl)-N^{6}$-methyladenines were synthesized, starting from 2-amino-6-chloropurine using palladium-catalyzed coupling as a key step as potential adenosineo receptor ligand.
Bibliography:KISTI1.1003/JNL.JAKO200111921098903
ISSN:0253-6269
1976-3786