다발성대칭성지방종증의 1예

• Published in: Tuberculosis and respiratory diseases Vol. 47; no. 1; pp. 97 - 102
• Main Authors: 윤수미, 김연수, 김진호, 이동석, 최진원, 양석철, 윤호주, 신동호, 김태화, 최요원, 박성수, Yoon, Su-Mi, Kim, Yeon-Soo, Kim, Jin-Ho, Lee, Dong-Suck, Choi, Jin-Won, Yang, Seok-Chul, Yoon, Ho-Joo, Shin, Dong-Ho, Kim, Tae-Wha, Choi, Yo-Won, Park, Sung-Soo
• Format: Journal Article
• Language: Korean
• Published: 1999
• Subjects: Multiple symmetric lipomatosis
• ISSN: 1738-3536; 2005-6184

Multiple symmetric lipomatosis(Madelung's disease) seems to represent a relatively common disease in Europe but has not been described in the Korean literature. It is characterized by highly typical symmetric deposits of subcutaneous fat on the neck, arms, and upper part of the trunk. The localized increase of adipose tissue is hyperplastic in nature and probably results from a local defect in adrenergic stimulated lipolysis. Multiple symmetric lipomatosis is frequently, but inconstantly, associated with alcoholism, liver disease, glucose intolerance, and hyperuricemia, but their etiologic role remains to be established. Clinical importance is the apparent high incidence of malignant tumors of the upper airways requiring through ear, nose, and throat and internal examination of all patients. Another importance is possibility of airway obstruction due to mass effect. Dietary treatment and weight loss are of limited value. Surgical treatment gives only temporary relief and should be restricted to patients with functional impairment. We report a case of a 63-year-old man with multiple symetric lipomatosis and alcoholism. 다발성대칭성지방종증은 드문 질환이나 그 임상양상이 독특하여 진단이 어렵지는 않으나 증상이 없고 문헌에 잘 소개되지 않아 진단을 하지 못하는 경우가 있을 것으로 생각된다. 또한 다른 대사질환이나 악성종양을 동반하는 경우가 있어서 이에 대한 관심이 필요하며 지방종이 인후나 기관을 누르는 경우 호흡곤란을 유발하기도 하고, 종격동등 심부 조직에 침투하는 경우 예후가 나쁠 수 있다. 국내에서 극히 드문 다발성 대칭성지방종증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.