Cytotoxic Constituents form the Roots of Anthriscus sylvestris

Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolated and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the ch...

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Bibliographic Details
Published inArchives of pharmacal research Vol. 22; no. 2; pp. 208 - 212
Main Authors Lim, Young-Hee, Leem, Moon-Jeong, Shin, Dong-Hyuk, Chang, Hwan-Bong, Hong, Seung-Woo, Moon, Eun-Yi, Lee, Dug-Keun, Yoon, Sung-June, Woo, Won-Sick
Format Journal Article
LanguageKorean
Published 1999
Subjects
Anthriscus sylvestis
Anti-tumor agents
Cytotoxic lignans
Angeloyl podophyllotoxin
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Summary:Activity-guided fractionation of the roots of Anthriscus sylvestris resulted in the isolated and characterization of five cytotoxic compounds, deoxypodophyllotoxin (1), falcarindiol (2), and angeloyl podophyllotoxin (5) from the hexane soluble fraction and morelensin (3), bursehernin (4) from the choloroform soluble fraction. It is the first report of the occurrence of compound 5 in nature.
Bibliography:KISTI1.1003/JNL.JAKO199911919477736
ISSN:0253-6269
1976-3786