유기용제의 생물학적 폭로기준 설정에 관한 연구

• Published in: 한국산업위생학회지 Vol. 1; no. 2; pp. 192 - 199
• Main Authors: 장재연, 전향숙, 정호근, Jang, Jae Yeon, Chun, Hyang Sook, Chung, Ho Keun
• Format: Journal Article
• Language: Korean
• Published: 1991
• Subjects: MEK; Toluene; Perchloroethylene; Biological exposure index
• ISSN: 1226-4326

Biological exposure indices (BEI) of toluene, perchloroethylene (PCE) and methyl ethyl ketone (MEK) for Korean workers were studied respectively. Environmental exposures in workplace to organic solvent were measured by personal sampling. Blood toluene, blood perchloroethylene, urinary trichloroacetic acid and urinary MEK were determined by headspace gas chromatography. Urinary hippuric acid were determined by HPLC and corrected by creatinine. BEIs for Korean workers were calculated as the levels of determinants which are correspond to permissible exposure limits in Korea. Blood toluene level of 2.2mg/l and urinary hippuric acid level of 1.7g/g creatinine are correspond to an exposure of 100 ppm toluene. Blood PCE concentration of 1.6mg/l and urinary trichloroacetic acid concentration of 2.9mg/l are correspond to an exposure of 50ppm PCE. Urinary MEK concentration of 1.0mg/l is correspond to an exposure of 200ppm of MEK. BEIs for Korean workers determined in this study are very different to ACGIH's BEI as urinary determinants are much lower and blood determinants are much higher than ACGIH's BEI.