Focused Issue : Thiazolidinedione 최신지견

Thiazolidinedione (TZD) is an insulin sensitizer that improves insulin resistance in the adipose tissue, liver, and muscles and has a pancreas-protective effect while inhibiting gluconeogenesis. Its other advantages include a glucose lowering effect, its durability, cardiovascular benefit, and recen...

Full description

Saved in:
Bibliographic Details
Published in당뇨병(JKD) Vol. 22; no. 2; pp. 97 - 104
Main Authors 김원준, Won Jun Kim
Format Journal Article
LanguageKorean
Published 대한당뇨병학회 30.06.2021
Subjects
Diabetes mellitus
Hypoglycemic agents
Pioglitazone
Thiazolidinediones
type 2
Online AccessGet full text

Cover

More Information
Summary:Thiazolidinedione (TZD) is an insulin sensitizer that improves insulin resistance in the adipose tissue, liver, and muscles and has a pancreas-protective effect while inhibiting gluconeogenesis. Its other advantages include a glucose lowering effect, its durability, cardiovascular benefit, and recent evidence in nonalcoholic fatty liver disease and dementia. However, there are also concerns about fluid retention/ edema/heart failure, bladder cancer, and fractures with TZD use. TZD can still be a useful option for diabetes treatment when calculating risk versus benefit, but appropriate selection of patients is needed.
Bibliography:Korean Diabetes Association
ISSN:2233-7431