Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study

• Published in: The Korean journal of internal medicine Vol. 36; no. S1; pp. 90 - 98
• Main Authors: Woo-hyuk Song, Eun Hui Bae, Jeong Cheon Ahn, Tae Ryom Oh, Yong-hyun Kim, Jin Seok Kim, Sun-won Kim, Soo Wan Kim, Kyung-do Han, Sang Yup Lim
• Format: Journal Article
• Language: Korean
• Published: 대한내과학회 01.03.2021
• Subjects: Coronary artery disease; Mortality; Obesity
• ISSN: 1226-3303; 2005-6648

Background/Aims: We investigated the impact of obesity on the clinical outcomes following percutaneous coronary intervention (PCI). Methods: We included South Koreans aged > 20 years who underwent the Korean National Health Screening assessment between 2009 and 2012. Obesity was defined using the body mass index (BMI), according to the World Health Organization’s recommendations. Abdominal obesity was defined using the waist circumference (WC), as defined by the Korean Society for Obesity. The odds and hazard ratios in all-cause mortality were calculated after adjustment for multiple covariates. Patients were followed up to the end of 2017. Results: Among 130,490 subjects who underwent PCI, the mean age negatively correlated with BMI. WC, hypertension, diabetes, dyslipidemia, fasting glucose, total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels correlated with the increased BMI. The mortality rates were higher in the lower BMI and WC groups than the higher BMI and WC groups. The non-obese with abdominal obesity group showed a mortality rate of 2.11 per 1,000 person-years. Obese with no abdominal obesity group had the lowest mortality rate (0.88 per 1,000 person-years). The mortality showed U-shaped curve with a cut-off value of 29 in case of BMI and 78 cm of WC. Conclusions: The mortality showed U-shaped curve and the cut-off value of lowest mortality was 29 in case of BMI and 78 cm of WC. The abdominal obesity may be associated with poor prognosis in Korean patients who underwent PCI.