Recent advances in transarterial embolotherapies in the treatment of hepatocellular carcinoma

• Published in: Clinical and molecular hepatology Vol. 23; no. 4; pp. 265 - 272
• Main Authors: Edward Wolfgang Lee, Sarah Khan
• Format: Journal Article
• Language: Korean
• Published: 대한간학회 31.12.2017
• Subjects: Bland embolization; Hepatocellular carcinoma; Radioembolization; Selective internal radiation therapy; Transarterial chemoembolization; Yttrium-90
• ISSN: 2287-2728; 2287-285X

Management of hepatocellular carcinoma (HCC) can be maximized with the utilization of multiple treatment modalities including transplant, surgical resection and locoregional therapies including ablative therapies and transarterial embolotherapies. Although transplant and surgical resection offer the best clinical outcomes, a limited number of patients are amenable to these surgical treatment options due to the advanced disease at presentation. Transarterial embolotherapies including conventional transarterial chemoembolization (cTACE), bland transarterial embolization (TAE), drug-eluting beads transarterial chemoembolization (DEB-TACE) and selective internal radiation therapy (SIRT) with Yttrium 90 ( 90 Y) have played an increasingly important role for these patients with unresectable HCC. With a better understanding of different transarterial embolotherapies, more personalized and precise treatment should be implemented for these patients with unresectable HCC. In this review, the updated evidence on the current role of each embolotherapy in the treatment of HCC is summarized. (Clin Mol Hepatol 2017;23:265-272)