Contributed Mini Review : Role of Wnt signaling in fracture healing

The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summ...

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Bibliographic Details
Published inBMB reports Vol. 47; no. 12; pp. 668 - 674
Main Authors Hui Yun Xu, Jing Duan, Dan Dan Ning, Jing Bao Li, Ruo Fei Liu, Rui Xin Yang, Jean X Jiang, Peng Shang
Format Journal Article
LanguageKorean
Published 생화학분자생물학회 31.12.2014
Subjects
Fracture healing
GSK-3β
Sost
Wnt signaling pathway
β-catenin
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Summary:The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summarize recent research progress in the area, which may be conducive to the development of Wnt-based therapeutic strategies for bone repair.
Bibliography:Korean Society for Biochemistry and Molecular Biology
ISSN:1976-6696